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However, there are certain classes of diuretic which usually fall into this category, such as the thiazides. Diuretics are used to treat oedema in heart failure, liver cirrhosis, hypertension and certain kidney diseases. Some diuretics, such as acetazolamide, make the urine more alkaline and are helpful in increasing excretion of substances such as aspirin in cases of overdose.

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Regulation of anti-diuretic hormone secretion is primarily through the plasma osmolarity. Osmolarity is sensed in the hypothalamus by neurons known as osmoreceptors, which in turn stimulate secretion from those neurons that produce anti-diuretic hormone. Secretion of anti- diuretic hormone is where To Order Floxin Online Safe simulated by decreases in blood Moduretic Online France conditions sensed by stretch receptors in the heart and large arteries.

Changes in blood pressure and volume are not nearly as sensitive a stimulator as increased osmolarity, but are nonetheless potent in severe conditions. Another potent stimulus of anti-diuretic hormone is nausea and vomiting, both of which are controlled by regions in the brain with links to the hypothalamus. The most common disease state related to anti-diuretic hormone is diabetes insipidus. This condition can arise from either of two situations: The major indication of either type of diabetes insipidus is excessive urine production; as much as 16 l of urine per day.

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